Introduction FOP
Introduction to Fibrodysplasia ossificans progressiva (FOP, Münchmeyer syndrome) Fibrodysplasia ossificans progressiva (FOP, Münchmeyer syndrome) First mentioned in England around 1740 Orphan disease, approx. one patient per 2 million individuals Approx. 600 cases are documented Autosomal dominant Average life span: 45 years Early indicator: deformed big toes Progressive incidents of inflammation, followed by differentiation of inflamed…