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The mechanisms of disturbances

Introduction to Fibrodysplasia ossificans progressiva (FOP) In 2006, a landmark study showed that a point mutation in the ALK2 receptor is linked to FOP (Shore et al., 2006) ACVR1/ALK2 is part of the family of type I BMP receptors (BMPRs) BMPRs play a crucial role in bone formation during development The study suggests that the…